IOVA

IOVA

Iovance Biotherapeutics, Inc.

Company Information

SectorHealthcare
IndustryBiotechnology
Market Cap$6.38B
Analysts Rating2.3/5

Recommendation Details

PortfolioLargecap
DateOct 29, 2026
ForecastQ Daily Probabilities
57.5%
75.6%
62.3%

Company Description

Iovance Biotherapeutics, Inc., a biotechnology firm currently in the clinical development stage, is committed to discovering and bringing to market cancer immunotherapy solutions. Its core mission involves leveraging the patient's own immune system to effectively combat and eradicate cancerous cells. The company is presently conducting six Phase 2 clinical trials. These include study C-144-01, evaluating its primary experimental compound, lifileucel, for individuals with advanced melanoma. Another trial, C-145-04, is assessing lifileucel's potential for treating cervical cancer that is recurrent, metastatic, or persistent. Additionally, investigational product LN-145 is undergoing evaluation in trial C-145-03 for recurrent and/or metastatic head and neck squamous cell carcinoma. Iovance Biotherapeutics, Inc. maintains strategic alliances and licensing arrangements with several distinguished entities, including H. Lee Moffitt Cancer Center, M.D. Anderson Cancer Center, Ohio State University, the Centre hospitalier de l'Université de Montreal, Cellectis S.A., and Novartis Pharma AG. Established in 2007, the company was previously known as Lion Biotechnologies, Inc. It adopted its current name, Iovance Biotherapeutics, Inc., in June 2017. Its corporate offices are located in San Carlos, California.

Recent News & Events

Positive lung-cancer data and webcast drive a sharp near-term rally, with Q3 results on Nov 5 as the next major binary catalyst.

POSITIVEOct 28, 2026
Clinical Data Readout

Positive lung-cancer data for lifileucel; webcast scheduled

Iovance announced positive results for one-time lifileucel TIL therapy from the IOV-LUN-202 Phase 2 registrational cohorts in previously treated nonsquamous mNSCLC, with a webcast on Oct 29 to discuss the data and precision-medicine strategy. The news drove a ~15% premarket/early move on heavy relative volume, expanding the perceived addressable market beyond melanoma and supporting near-term momentum.

Yahoo Finance / StockTwits
NEUTRALOct 27, 2026
Earnings Announcement (Scheduled)

Q3 2026 results scheduled for November 5

Iovance will report Q3 2026 financial results and corporate updates on Nov 5, 2026. With recently raised full-year revenue guidance of $410-420M, the print and any guidance commentary are a key near-term binary event for the stock.

GlobeNewswire / Company Press Release
POSITIVESep 29, 2026
Guidance Raise

Full-year 2026 revenue guidance raised to $410-420M

Iovance raised FY2026 total revenue guidance to $410-420M, a ~$55M midpoint increase (~15%) over the prior $350-370M range, citing strong U.S. demand for Amtagvi and Proleukin. The raise, while slightly older, underpins the upcoming Q3 print and reinforces the growth narrative supporting the stock.

Company Press Release (IR)
POSITIVEOct 26, 2026
Clinical Data Readout

Sarcoma pilot trial shows 50% response rate

Early results in UPS and DDLPS soft tissue cancers showed 4 of 8 evaluable patients with confirmed partial responses (50% ORR), all ongoing at cutoff, with safety consistent with prior lifileucel regimens. The data support the Phase 2 Saratoga registrational trial and add to the broader TIL platform momentum.

Yahoo Finance / StockTwits

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